Primary Identifier | MGI:5308064 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Cd207 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A cDNA encoding cre recombinase with a bovine polyadenylation sequence and a nuclear localization signal (NLS) and followed by an Frt-flanked neo cassette was inserted into exon 2 of Cd207 (langerin) by homologous recombination. After verifying germline transmission, the neo resistance cassette was deleted from the allele by breeding founders to FLPe-expressing mice. |