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Allele : Tnni3<tm1.1Jdp> troponin I, cardiac 3; targeted mutation 1.1, James Potter
Primary Identifier  MGI:5308372 Allele Type  Targeted
Attribute String  Dominant negative, Humanized sequence, Inserted expressed sequence Gene  Tnni3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A C to T transition in codon 21 changed the encoded amino acid from arginine to cysteine. In addition, a floxed neo cassette was inserted in intron 3. Subsequent cre-mediated excision removed the neo selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • R21C+,
  • R21C+
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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