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Allele : Mirc21<tm1.1Lhe> microRNA cluster 21, including Mir34c through Mir34b; targeted mutation 1.1, Lin He

Primary Identifier  MGI:5308794 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mirc21
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of Mir34b and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of Mir34c. Cre-mediated recombination removed the neo cassette and both microRNAs. Real-time PCR confirmed the absence of transcript expression in mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • miR-34bc<->,
  • miR-34bc<->,
  • Mirc21<tm1.1Ghan>,
  • Mir34b/Mir34c<tm1.1Ghan>,
  • Mir34b/Mir34c<tm1.1Ghan>,
  • Mirc21<tm1.1Ghan>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele