|  Help  |  About  |  Contact Us

Allele : Mfrp<rdx> membrane frizzled-related protein; retinal degeneration x

Primary Identifier  MGI:5312653 Allele Type  Spontaneous
Attribute String  Null/knockout Gene  Mfrp
Inheritance Mode  Recessive Strain of Origin  129S-Per3<tm1Drw>/J
Is Recombinase  false Is Wild Type  false
description  This mutation was originally identified in mice carrying Per3tm1Drw on a 129 background.
molecularNote  A spontaneous mutation resulted in the the deletion of a single G nucleotide from the GGGGG sequence in exon 3. This mutation causes a frame shift and premature stop codon in the first third of the 14 predicted exons. Western blot analysis confirmed the absence of protein expression in whole eyecups.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Mfrp<174delG>,
  • Mfrp<174delG>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele