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Allele : Tmc1<nice> transmembrane channel-like gene family 1; nice

Primary Identifier  MGI:5314995 Allele Type  Chemically induced (ENU)
Gene  Tmc1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  ENU induced a T to C mutation at position 1345 resulting in a tyrosine to histidine substitution at amino acid 449 in exon 13 and is predicted to disrupt transmembrane domain 4. Protein expression is reduced in the type III fibrocytes basal to mid cochlear region in homozygous mice.
  • mutations:
  • Single point mutation
  • synonyms:
  • Tmc1<Y449H>,
  • Tmc1<Y449H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele