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Allele : Gt(ROSA)26Sor<tm8(Hoxd11)Amc> gene trap ROSA 26, Philippe Soriano; targeted mutation 8, Andrew P McMahon
Primary Identifier  MGI:5315142 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129 and C57BL/6 and CBA and Swiss Webster
Is Recombinase  false Is Wild Type  false
description  ES cell line = YFP3.1, a male ES cell line carrying Tg(CAG-cre/Esr1*)5Amc and is compound heterozgous at Gt(ROSA)26Sor: Gt(ROSA)26Sortm1Sor and Gt(ROSA)26Sortm1(EYFP)Cos.
molecularNote  A cassette containing Hoxd11-IRES2-nlslacZ was inserted into the Gt(ROSA)26Sor locus via homologous recombination in YFP3.1 ES cells. The inserted cassette has a floxed PGK-neo STOP sequence preceding it, preventing Hoxd11 or lacZ transcription unless cre-mediated excision of the STOP has taken place. Targeted ES cells were injected into C57BL/6J blastocysts. This line was maintained on a C57BL/6J background.
  • mutations:
  • Insertion
  • synonyms:
  • R26Hoxd11,
  • R26Hoxd11
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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