Primary Identifier | MGI:5317113 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lgi1 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 6. A floxed neo cassette was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette and exons 6 and 7. Western blot analysis confirmed the absence of protein expression in the brain and spine. |