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Publication : ski can cause selective growth of skeletal muscle in transgenic mice.

First Author  Sutrave P Year  1990
Journal  Genes Dev Volume  4
Issue  9 Pages  1462-72
PubMed ID  2253874 Mgi Jnum  J:184590
Mgi Id  MGI:5424885 Doi  10.1101/gad.4.9.1462
Citation  Sutrave P, et al. (1990) ski can cause selective growth of skeletal muscle in transgenic mice. Genes Dev 4(9):1462-72
abstractText  We have created several lines of mice that contain a truncated chicken c-ski cDNA linked to an MSV LTR promoter. Adult mice from three independent lines show large increases in skeletal muscle. All three lines of mice express high levels of c-ski mRNA and protein in skeletal muscle. All other tissues examined show little or no expression of the c-ski transgene. The muscles of one of the three lines were examined in more detail. Type II fast fibers undergo selective hypertrophy in affected muscles of this line.
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