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Allele : Gnas<tm1.2Plag> GNAS complex locus; targeted mutation 1.2, Antonius Plagge

Primary Identifier  MGI:5320901 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gnas
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-meditated recombination inverted the exon 2SA and lacZ leaving a lox2272 site at the 5' end and loxP site at the 3' end. The allele expresses a fusion product between the XL domain and lacZ. qRT-PCR confirmed a 90% downregulation of transcript expression.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele