Primary Identifier | MGI:5427086 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gpm6a |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was replaced with a floxed PGK-neomycin selection cassette. The selection cassette was removed from properly targeted mice by cr excision. Removal of exon 2 causes a downstream frame shift and only short, non-functional, N-terminal peptides ar produced. |