Primary Identifier | MGI:5427934 | Allele Type | Targeted |
Attribute String | Humanized sequence, Hypomorph | Gene | Gata4 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A G to A mutation was introduced in exon 3 creating a glycine to serine substitution (G295S) and a floxed neo cassette was inserted downstream of exon 4 via homologous recombination. Immunoblot analysis indicated that protein levels in homozygous mice are similar to wild-type. |