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Allele : b2b243Clo Mutant line 243; Bench to Bassinet Program (B2B/CVDC), mutation 243 Cecilia Lo
Primary Identifier  MGI:5430049 Allele Type  Chemically induced (ENU)
Gene  b2b243Clo Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  B2B/CvDC
description  Summative Diagnosis:
Mutant Type 1: Cardiac phenotype: Persistant truncus arteriosus (PTA) with right aortic arch
Mutant Type 2: Non-cardiac phenotype: Cystic kidney and hydronephrosis

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
2720 Right aortic arch
0500 Truncus arteriosus
4502 Hydronephrosis
4508 Polycystic kidney disease

molecularNote  This ENU-induced mutation line was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See b2b243.1Clo and b2b243.1Clo.
  • synonyms:
  • Jupiter,
  • Jupiter
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Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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