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Allele : Trp53<tm1.1Wgu> transformation related protein 53; targeted mutation 1.1, Wei Gu

Primary Identifier  MGI:5431727 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129S6/SvEvTac Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 4 was replaced with a modified exon 4 in which nucleotide substitutions (AG-to-GA) result in the amino acid substitution of lysine with arginine at position 117 (p.K117R). A loxP site flanked neomycin resistance gene cassette inserted downstream of the modified exon 4 was removed by Cre-mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • p53<K117R>,
  • p53<K117R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele