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Allele : Itgb1<tm13.1Ref> integrin beta 1 (fibronectin receptor beta); targeted mutation 13.1, Reinhard Fassler
Primary Identifier  MGI:5430791 Allele Type  Targeted
Attribute String  Not Specified Gene  Itgb1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted downstream of a modified exon 16 in which nucleotide substitutions result in the amino acid substitutions of alanine for threonine at positions 788 and 789 (T788A and T789A). This amino acid substitutions prevent Kindlin (Fermt) binding. Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • beta1 TT/AA,
  • beta1 TT/AA
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

6 Publication categories

Trail: Allele




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