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Allele : Tg(Erv4-cre/ERT2*)657Slp transgene insertion 657, Samuel L Pfaff
Primary Identifier  MGI:5431581 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Erv4-cre/ERT2*)657Slp
Strain of Origin  BALB/c and C57BL/6 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  The 5' LTR of murine endogenous retrovirus with leucine tRNA primer (MuERV-L; MERVL; Erv4) and the primer binding site drive expression of tamoxifen-inducible Cre recombinase (2C::ERT2-Cre-ERT2). Two flanking ERT2 segments were inserted to make Cre activation less leaky. The transgenic vector was injected into CB6 (BALB/c and C57BL/6) embryos and the resultant strain was subsequently maintained on the same mixed genetic background by the donating laboratory. This is founder line 657.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(MuERV-L-ERT2-Cre-ERT2)657Slp,
  • Tg(MuERV-L-ERT2-Cre-ERT2)657Slp,
  • 2C::ERT2-Cre-ERT2,
  • 2C::ERT2-Cre-ERT2
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0 Mutation Involves

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