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Allele : Apc<tm1.1Klne> APC, WNT signaling pathway regulator; targeted mutation 1.1, Kristi L Neufeld

Primary Identifier  MGI:5431889 Allele Type  Targeted
Gene  Apc Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitutions replaced six amino acids in two nuclear localization sequences (NLS1 and NLS2) by substitution of alanine for lysine. A self-excising neo cassette was inserted into the last intron and removed itself properly.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Apc<mNLS>,
  • Apc<mNLS>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele