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Allele : Gt(ROSA)26Sor<tm3(CAG-flpo/ERT2)Alj> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Alexandra L Joyner
Primary Identifier  MGI:5432216 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
description  ES cell line = CY2.3 (129S6/SvEvTac-derived: gift of Rockefeller Gene Targeting Core)
molecularNote  The sequence encoding a FLPo/ERT2 fusion protein (optimized FLP recombinase fused to the tamoxifen-responsive mutated human estrogen receptor ligand-binding domain), SV40 polyadenylation site and a loxP-flanked PGK-neo cassette was cloned downstream of the human CMV enhancer/chicken ACTB promoter (CAG). This construct was targeted to the Gt(ROSA)26Sor locus in embryonic stem cells.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm3(ACTB-FLPo/ERT2)Alj>,
  • R26<FlpoER>,
  • Gt(ROSA)26Sor<tm3(ACTB-FLPo/ERT2)Alj>,
  • R26<FlpoER>
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0 Mutation Involves

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