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Allele : Gpx4<tm3Marc> glutathione peroxidase 4; targeted mutation 3, Marcus Conrad

Primary Identifier  MGI:5433757 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Gpx4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An inframe translation STOP was introduced into the mitochondrial leader sequence (TTAA to ATTAATTC). A recombinase flanked neo cassette was inserted downstream of exon 7. Western blot analysis confirmed the absence of mitochondria specific isoform in the testes.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • mGPx4<->,
  • mGPx4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele