Primary Identifier | MGI:5437711 | Allele Type | Targeted |
Gene | Havcr1 | Transmission | Germline |
Strain of Origin | B6.Cg-Thy1<a> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 3 was replaced with a pgk-neo cassette via homologous recombination. Western blot analysis detected the expression of a shortened protein in heterozygous mice. These shortened proteins lacking the O-glycosylated mucin domain are expressed on the surface of B cells. |