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Allele : b2b1146Clo Mutant line 1146; Bench to Bassinet Program (B2B/CVDC), mutation 1146 Cecilia Lo
Primary Identifier  MGI:5437084 Allele Type  Chemically induced (ENU)
Gene  b2b1146Clo Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  B2B/CvDC
description  Summative Diagnosis:
Cardiac defects: Complex congenital heart disease associate with heterotaxy, such as Taussig-Bing type double outlet right ventricle (DORV) associated with dextrocardia or dextroversion, atrioventricular septal defect (AVSD)
Noncardiac phenotype: Right and left lung isomerism, immotile/abnormal airway cilia dysmotility, kidney cysts

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
0110 Dextrocardia
0190 Heterotaxy Syndrome
0610 DORV, Taussig bing
0700 D-loop transposition of the great arteries
0720 D-loop TGA with ventricular septal defect
1110 Atrioventricular canal (endocardial cushion defect)
3804 Congenital heart disease
3950 {S,D,D}
3968 {I,D,D}
4508 Polycystic kidney disease

molecularNote  This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
  • synonyms:
  • Hanson,
  • Hanson
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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