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Allele : Fgf10<tm1.1(cre/ERT2)Sbel> fibroblast growth factor 10; targeted mutation 1.1, Saverio Bellusci

Primary Identifier  MGI:5438701 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Fgf10
Transmission  Germline Strain of Origin  C57BL/6
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
description  allele made by GenOway
molecularNote  A targeting construct containing a cassette with the cre/ERT2 sequence followed by an IRES-YFP-polyA-neo fragment was injected into TVB2 ES cells. Homologous recombination intoduced the construct in frame with the ATG start codon of the Fgf10 exon 1. Chimeric animals were crossed to Flp-expressing mice to delete the neo selection cassette. It is a loss-of-function allele for Fgf10.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Fgf10Cre-ERT2,
  • Fgf10<iCre>,
  • Fgf10<iCre>,
  • Fgf10Ki-v1,
  • Fgf10Cre-ERT2,
  • Fgf10Ki-v1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

12 Publication categories

Trail: Allele