Primary Identifier | MGI:5439291 | Allele Type | Targeted |
Attribute String | Inducible | Gene | Htr1b |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Induced With | doxycycline/tetracycline | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Flexible Accelerated STOP Tetracycline Operator (tetO)-knockin (FAST) was used to insert a construct containing a loxP site, FRT site, neo cassette, STOP, FRT site, tetracycline operator (tetO) and loxP site was inserted upstream of the translation initiation site. Recombination removed the neo/STOP cassette and allows for tetO driven expression of the endogenous gene. |