Primary Identifier | MGI:5440845 | Allele Type | Targeted |
Gene | Pcdhg | Transmission | Germline |
Strain of Origin | 129S4/SvJae | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The genomic sequence encoding Pcdhga1, Pcdhga2 and Pcdhga3 was replaced with a hygro cassette flanked with lox2272 sites. Cre-mediated recombination removed the hygro cassette. By deleting the 3 alpha exons, this allele is a knock-out of three A-type isoforms (TAKO). |