| Primary Identifier | MGI:5439663 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Psen1 |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 6 was replaced with one in which a point mutation (CTT to CCT) results in the amino acid substitution of proline for leucine at position 166 (L166P), mimicking a mutation found in some familial Alzheimer disease (FAD) patients. Cre-mediated recombination removed the floxed neo cassette. |
