| Primary Identifier | MGI:5443906 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Grn |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site and FRT flanked neo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 4 via homologous recombination. Cre mediated recombination deleted exons 2 - 4. qRT-PCR and immunoblot analysis confirmed the absence of full length RNA and protein expression in the brains from homozygous mice. |
