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Allele : Scn5a<tm3(SCN5A*)Rdn> sodium channel, voltage-gated, type V, alpha; targeted mutation 3, Dan M Roden

Primary Identifier  MGI:5445892 Allele Type  Targeted
Attribute String  Inserted expressed sequence, RMCE-ready Gene  Scn5a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Recombinase-mediated cassette exchange was used to replace exon 2 with a loxP site, the FLAG-tagged full length human SCN5A with a G to A mutation (c.3823G to A), an FRT-flanked hygro cassette and a loxP site. The mutation results in the amino acid substitution of asparagine for aspartic acid at position 1275 (D1275N).
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • DN,
  • DN
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele