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Allele : Tg(Vav1-Lin28b)C3Apla transgene insertion C3, Peter Aplan

Primary Identifier  MGI:5446657 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Vav1-Lin28b)C3Apla
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) (J:189197).
molecularNote  The murine Lin28b cDNA was inserted into the HS 21/45-vav vector containing 3' and 5' Vav1-regulatory elements. The Vav1-regulatory elements target expression of Lin28b to hematopoietic tissues. Transgenic mRNA is expressed in the bone marrow, spleen and thymus. Three lines were made, C3, D4, and D10.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele