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Allele : Kdm6a<tm2.1Kaig> lysine (K)-specific demethylase 6A; targeted mutation 2.1, Kai Ge
Primary Identifier  MGI:5448826 Allele Type  Targeted
Gene  Kdm6a Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 24 was replaced with a loxP site flanked modified exon 24 in which nulceotide substitutions result in the amino acid substitution of histidine with alanine and glutamic acid at positions 1146 and 1148 (H1146A and E1148A). Flp-mediated recombination removed the FRT site flanked neomycin resistance gene cassette inserted downstream of the modified exon 24. The modified exon 24 remains floxed.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • UTX<KI>,
  • UTX<KI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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