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Allele : Il7<tm1.1Iku> interleukin 7; targeted mutation 1.1, Koichi Ikuta

Primary Identifier  MGI:5461069 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Il7
Transmission  Germline Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Murine BAC clone RP23-446B12 was modified by the insertion of EGFP cDNA and a floxed neomycin resistance cassette after a translation initiation codon in exon 1. The 8 kb homologous recombination targeting vector was then recovered from the modified BAC and used to generate this allele. The selection cassette was then excised by transient cre expression. GFP expression was detected in thymic stromal cells.
  • mutations:
  • Insertion
  • synonyms:
  • Il-7<GFP>,
  • Il-7<GFP>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele