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Allele : Lrrk2<tm3.1Mjff> leucine-rich repeat kinase 2; targeted mutation 3.1, The Michael J Fox Foundation
Primary Identifier  MGI:5466853 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Lrrk2
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to introduce an alanine to threonine (A2016T) substitution at codon 2016 of exon 41. An FRT-flanked neomycin cassette was introduced 400 bp downstream of exon 41. FLP recombinase mediated recombination removed the neo cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • LRRK2-A2016T,
  • LRRK2-A2016T
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele




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