Primary Identifier | MGI:5463979 | Allele Type | Targeted |
Attribute String | Modified regulatory region | Gene | Rr123 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The Smad3-binding site (CAGACtGTCTG) in enhancer CNS1 in an intron of Foxp3 was deleted. The loxP site flanked neomycin resistance gene cassette that was inserted downstream was removed through subsequent cre-mediated recombination. |