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Allele : Tg(SFTPC-cre/ERT2)F42Kfx transgene insertion F42, Kai-Feng Xu

Primary Identifier  MGI:5465199 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(SFTPC-cre/ERT2)F42Kfx
Strain of Origin  C57BL/6J Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A 9.5 kb construct encoding SFTPC-cre/ERT2 (human surfactant associated protein C gene driving cre fused to a mutated estrogen receptor sequence; ERT2) was microinjected into mouse embryos to generated transgenic mice. Five founders were generated, but cre/ERT2 protein was stably expressed after tamoxifen injection by the progeny of only 2 lines, F42 and F67. These two lines were propagated for further experiments. Line F42 was entered as a representative line.
  • mutations:
  • Insertion
  • synonyms:
  • SPC-Cre-ER<T2>,
  • SPC-Cre-ER<T2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele