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Allele : Cx3cr1<tm2.1(cre/ERT2)Jung> C-X3-C motif chemokine receptor 1; targeted mutation 2.1, Steffen Jung
Primary Identifier  MGI:5467985 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Cx3cr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A cre/ERT2 cassette with a floxed neo gene was inserted by RedE/T recombineering into a BAC containing the Cx3cr1 locus, replacing the coding exon of Cx3cr1. Properly targeted ES cells were aggregated with 8-cell embryos to generate chimeras. Chimeras were backcrossed to C57BL/6 mice. Tne neo was excised by crossing the animals to a cre deleter strain (Tg(Pgk1-cre)1Lni).
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cx3cr1<creER>,
  • Cx3cr1<creER>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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239 Publication categories

Trail: Allele




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