| Primary Identifier | MGI:5463442 | Allele Type | Chemically induced (ENU) |
| Attribute String | Altered localization | Gene | Fras1 |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6JAnu |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The mutation has been identified as a T to C transition at position 10762 of the cDNA sequence, in a region derived from exon 69, that substitutes proline for serine at amino acid position 3588 (S3588P). Western blot analysis confirmed correct levels of protein expression. Immunohistochemistry confirmed the protein does not correctly localize to the basal membrane. |
