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Allele : Ndufs4<tm1Capt> NADH:ubiquinone oxidoreductase core subunit S4; targeted mutation 1, Carl A Pinkert

Primary Identifier  MGI:5464892 Allele Type  Targeted
Attribute String  Not Specified Gene  Ndufs4
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description  ES cell = PC1 (129S6/SvEvTac)
molecularNote  A point mutant construct with a floxed neo cassette created a 1-base deletion causing a frameshift and premature stop codon in the last exon upstream of a conserved 10 to 15 amino acid C-terminal sequence. Western blot analysis confirmed reduced expression of a truncated protein in heterozygous mice.
  • mutations:
  • Single point mutation,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele