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Allele : Pfn1<tm1Foxp> profilin 1; targeted mutation 1, Paul L Fox
Primary Identifier  MGI:5470084 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Pfn1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was floxed. A modified exon 3 with an A to T transversion that results in the amino acid substitution of phenylalanine for tyrsorine at position 129 (Y129F). Cre-mediated recombination is required to remove the wild-type exon 3 and allow for expression of the modified exon 3.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Pfn1<flox:Y129F>,
  • Pfn1<flox:Y129F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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