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Allele : Tg(CAG-Diaph3)771Lesp transgene insertion 771, Marci Lesperance
Primary Identifier  MGI:5468143 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CAG-Diaph3)771Lesp
Strain of Origin  FVB/NJ Is Recombinase  false
Is Wild Type  false
molecularNote  The insertion vector was approximately 7 kb, containing the CAG promoter and the Diaph3 complete coding sequence. Genotyping by PCR revealed that 10 of 83 potential transgenic founders had integrated the transgene. Five founders transmitted the transgene with offspring born in expected Mendelian ratios. Lines 771 and 924 exhibited hearing loss within the first 16 weeks of life in the F1 generation as detected by auditory brainstem response (ABR) testing and were selected for further analysis.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(CAG-Diap3)771Lesp,
  • Tg(CAG-Diap3)771Lesp
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