| Primary Identifier | MGI:5469354 | Allele Type | Spontaneous |
| Gene | Vps52 | Strain of Origin | wild-derived |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 3 nucleotide insertion of GGG is detected at the start of exon 2 in a stretch of consecutive G nucleotides (9 in the wild-type C57BL/6 sequence). The insertion of an additional G relative to Vps52t-w5 restores the reading frame to a wild-type reading frame. Western blot analysis with an antibody directed against amino acids 496-509 detects the protein band in kidney tissue from homozygous mice. This mutation is found in the tw5G haplotype. |
