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Allele : Acvr1<tm1Emsh> activin A receptor, type 1; targeted mutation 1, Eileen M Shore

Primary Identifier  MGI:5471642 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Acvr1
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
description  Chimeras analyzed in J:194134 contain 70% to 90% mutant cells.
molecularNote  A point mutation (CGC to CAC) results in the amino acid substitution of histidine for arginine at position 206 (R206H). An FRT-flanked neo cassette was inserted downstream of the modified exon 5.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Acvr1<R206H>,
  • Acvr1<R206H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele