Primary Identifier | MGI:5471642 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Acvr1 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
description | Chimeras analyzed in J:194134 contain 70% to 90% mutant cells. |
molecularNote | A point mutation (CGC to CAC) results in the amino acid substitution of histidine for arginine at position 206 (R206H). An FRT-flanked neo cassette was inserted downstream of the modified exon 5. |