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Allele : Igs86<tm1.1Low> intergenic site 86; targeted mutation 1.1, Malcolm J Low
Primary Identifier  MGI:5473422 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Igs86
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette was inserted between the first upstream neuronal enhancer (nPE1) and the deleted second neuronal enhancer (nPE2). Cre-mediated recombination removed the neo cassette and restored expression in the hypothalamic arcuate nucleus (Arc).
  • mutations:
  • Insertion
  • synonyms:
  • Pomc<tm2.1Low>,
  • Pomc<tm2.1Low>,
  • arcPomc<+>,
  • arcPomc<rcue>,
  • arcPomc<+>,
  • arcPomc<rcue>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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