Primary Identifier | MGI:5484565 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hltf |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site and F3 flanked puro cassette were inserted upstream of exon 11 and a loxP site was inserted downstream of exon 13 via homologous recombination. Recombinase mediated recombination removed the selection cassette and exons 11-13. Western blot analysis confirmed the absence of protein expression in the hippocampus of homozygous mice. |