| Primary Identifier | MGI:5485244 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Prkcz |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 11 was floxed. Cre-mediated recombination removed exon 11 and an FRT-flanked neo cassette inserted downstream of exon 11. Western blot analysis confirmed the absence of PKC-zeta and the isoform protein kinase M-zeta (PKM-zeta) in the brain. Protein expression of other PCK isoforms is normal. |
