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Allele : Palb2<tm1.2Dli> partner and localizer of BRCA2; targeted mutation 1.2, David M Livingston

Primary Identifier  MGI:5495930 Allele Type  Targeted
Attribute String  Null/knockout Gene  Palb2
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP site upstream of exon 2, and a second loxP site, followed by a frt-flanked neomycin resistance (neo) cassette, downstream of exon 3. Cre-mediated recombination removed exon 2, exon 3 and the neomycin reistance cassette. Western blot analysis confirmed the absence of transcript expression in ES cells.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Palb2<delta>,
  • Palb2<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele