| First Author | Lemonnier F | Year | 2010 |
| Journal | Patent Application US20100138936 A1 | Mgi Jnum | J:197820 |
| Mgi Id | MGI:5494644 | Citation | Lemonnier F, et al. (2010) Transgenic mice and use thereof as an experimental model. Patent Application US20100138936 A1 |
| abstractText | The invention relates to the use of an expression vector construction coding for the functional HLA-DPa103beta401 complex specifically identified by anti-HLA-DP antibodies, in order to create transgenic mice. The invention also relates to the use of the transgenic mice obtained, such as for the comparative preclinical study of efficacy of vaccine candidates in order to asses the risks associated with the unwanted induction of an autoimmune disease and in order to determine a therapeutic strategy. Also published as CA2600912A1, EP1856268A1, WO2006092515A1 |
