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Allele : Gt(ROSA)26Sor<tm2.1(CAG-PSTPIP1*)Dtg> gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Douglas T Golenbock
Primary Identifier  MGI:5496225 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted into the locus contained a CAG promoter that drives ubiquitous expression of the human cDNA with nucleotide substitutions that result in the amino acid substitution of threonine for alanine at position 230 (A230T) preceded by a floxed STOP cassette and followed by an IRES and the truncated human CD2 tag. Cre-mediated recombination removed the floxed STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa-26-PSTPIP1 A230T<STOP del>,
  • Rosa-26-PSTPIP1 A230T<STOP del>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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