Primary Identifier | MGI:5499177 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Erf |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette with a 5' loxP site was inserted upstream of the second coding exon. An additional loxP site was inserted downstream of the STOP codon in the fourth coding exon. RT-PCR confirmed reduced transcript expression. This allele is hypomorphic. |