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Allele : Nras<tm2.1Emfu> neuroblastoma ras oncogene; targeted mutation 2.1, Ernst-Martin Fuchtbauer
Primary Identifier  MGI:5502420 Allele Type  Targeted
Gene  Nras Transmission  Germline
Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  A floxed PGK/Tn5 neomycin resistance (neo) cassette and the Akv1-99 murine leukemia virus long terminal repeat were inserted into intron 1 via homologous recombination. The viral long terminal repeat was inserted at the proviral integration site 9 in the anti-sense direction. Cre-mediated recombination removed the neo cassette. Western blot analysis confirmed increased protein expression in the spleen and thymus.
  • mutations:
  • Insertion
  • synonyms:
  • LTR9NAS,
  • LTR9NAS
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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