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Allele : Scn3a<tm1.1Jwo> sodium channel, voltage-gated, type III, alpha; targeted mutation 1.1, John N Wood

Primary Identifier  MGI:5505505 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Scn3a
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct introduced loxP sites flanking exons 4 and 5 and a FRT-flanked neomycin resistance cassette following the second loxP site. The selection cassette was deleted by crossing mice carrying the original targeted allele with mice expressing flpe recombinase in the germline. Expression of Cre recombinase will delete 221 base pairs of the gene encompassing exon 4, intron 4 and exon 5.
  • mutations:
  • Insertion
  • synonyms:
  • floxed Nav1.3,
  • floxed Nav1.3,
  • Nav1.3 floxed,
  • Nav1.3 floxed
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele