| Primary Identifier | MGI:5504449 | Allele Type | Targeted |
| Gene | Sox3 | Transmission | Chimeric |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A 36 bp expansion of the first polyalanine tract expanded the tract from 14 to 26 alanines. Morula injection resulted in chimeras with up to 95% mutant cell contribution. In addition, an FRT flanked neo selection cassette was inserted downstream. Despite extensive breeding, none of these chimeras exhibited germline transmission of the mutant allele. |
