Primary Identifier | MGI:5506645 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd68 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to place an rtTA (reverse tetracycline regulated transactivator) and a loxP-flanked neomycin resistance (neo) cassette downstream of the transcriptional start site. Correctly targeted mice were bred to cre expressing mice to delete the neo cassette and the resulting offspring were bred together to remove the cre-expressing transgene. |